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Reading a COA — And Knowing What to Look For A Certificate of Analysis (COA) is the document that accompanies every lab-tested compound. It's meant to give you confidence in what you're working with. But not all COAs are created equal — and knowing how to read one is just as important as having one. What a basic COA includes: Compound name and lot/batch number Testing method used (e.g., HPLC, LC-MS, NMR) Purity percentage Date of analysis Lab name and signature What separates

Two Powerful Tools. Different Answers. Analytical chemistry isn't one-size-fits-all. Depending on what you need to know about a compound, different instruments give you different kinds of answers. Two of the most important in peptide and small molecule analysis are LC-MS and NMR — and understanding the difference helps you choose the right test. LC-MS (Liquid Chromatography-Mass Spectrometry) LC-MS separates the components of your sample and then measures the mass-to-charge

The Problem With "Purity Testing" Alone If you've ever ordered peptide testing and received a certificate showing 98% purity, you may have felt confident in that result. But here's what most people don't realize: a standard HPLC purity number tells you how much of something is in your sample — it doesn't confirm that the something is actually what you think it is. High-Performance Liquid Chromatography (HPLC) works by separating components in a sample based on how they inte

In today's fast-paced world, ensuring quality in products and services is more critical than ever. Companies are increasingly recognizing that relying on a single method of analysis may not provide the comprehensive insights needed to maintain high standards. This is where multimethod analysis comes into play. By integrating various analytical approaches, organizations can achieve a more nuanced understanding of their processes, leading to improved quality assurance outcomes

Peptide analysis is a crucial aspect of biochemistry and molecular biology, playing a significant role in various fields such as drug development, diagnostics, and proteomics. With the increasing complexity of biological systems, understanding peptides and their functions has become essential. This blog post will explore the techniques used in peptide analysis, their benefits, and how they contribute to advancements in science and medicine. What Are Peptides? Peptides are sho

Chemical analysis is at a pivotal point in its evolution, driven by advancements in technology and the increasing complexity of the substances we analyze. Among the various analytical techniques, Liquid Chromatography-Mass Spectrometry (LC-MS) stands out as a powerful tool that is transforming the landscape of chemical analysis. This blog post explores the future of LC-MS, highlighting the innovations that are shaping its development and the implications for various industrie